Stem Cell : Programming and Reprogramming

Conference Title

Location

Day Month Year

Speaker

Laurie A. Boyer

Laurie A. BoyerLaurie A. Boyer, Ph.D., received a doctorate in biochemistry from the University of Massachusetts Medical School in 2001. Her work with Craig Peterson focused on dissecting the biochemical mechanisms of chromatin remodeling enzymes. She then joined the laboratories of Rudolf Jaenisch and Rick Young at Whitehead Institute for Biomedical Research as a postdoctoral fellow. Dr. Boyer is a pioneer in the development of high-throughput platforms for genome wide analysis of transcription factor binding sites as well as histone modifications and chromatin regulators in stem cells. During her postdoctoral studies, she discovered how Oct4, Sox2, and Nanog comprise a core transcriptional regulatory network that controls embryonic stem cell (ESC) pluripotency. She also illuminated a key role for Polycomb group proteins in regulating cell fate decisions during ESC differentiation.  In 2006, Dr. Boyer was recognized as one of the world’s 50 top leaders in research, business or policy by Scientific American for her innovative work in understanding the genome of human ESCs. In 2007, she joined the faculty at the Massachusetts Institute of Technology as an assistant professor in the Biology Department. Dr. Boyer’s lab investigates how chromatin structure influences gene expression programs and ultimately cell fate and how failure to establish proper chromatin states can contribute to disease. In addition, her research team is interested in the role of noncoding RNA as well as non coding DNA elements in fine-tuning transcriptional programs during cell fate transitions.

Dr. Boyer is a Pew Scholar in the Biomedical Sciences and is the recipient of several early career awards including those from the Smith Family Foundation for Excellence in Biomedical Research as well as the Massachusetts Life Sciences Center.

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Supporting publications

Cell
Cell : Stem Cell
Trends in Pharmacological Sciences
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