Stem Cell : Programming and Reprogramming

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Speaker

Kevin Eggan

Kevin EgganDr. Eggan completed his bachelor’s degree in microbiology at the University of Illinois in 1996. After a two-year Predoctoral internship at Amgen at the National Institutes of Health in Bethesda, he enrolled at the graduate school of Massachusetts Institute of Technology in 1998. During his Ph.D. training, he actively pursued projects focused on cloning, stem cells and epigenetic reprogramming after nuclear transfer under the guidance of genetics pioneer, Dr. Rudolf Jaenisch. He stayed in the Dr. Jaenisch’s lab after his graduation for a one-year postdoc training in 2002. During that time, he also conducted a collaborative study with Dr. Richard Axel, a Nobel Prize winner at the Howard Hughes Medical Institute. In 2004, he moved to Harvard University as a junior fellow and then became an assistant professor of Molecular & Cellular Biology at the Stem Cell Institute in 2005.

Dr. Eggan has garnered international recognition for his seminal work and a number of high profile awards for his creativity and productivity, including the MacArthur Foundation “Genius Grant” in 2006. His current research focuses on applying the knowledge gained in stem cell biology to study the mechanisms underlying amyotrophic lateral sclerosis (ALS) and discover new therapeutic targets. He made a significant impact in the field by through the discovery that motor neurons derived from human embryonic stem cells are susceptible to the toxic effect of glial cells harboring an ALS mutation and that induced pluripotent stem (iPS) cells generated from adult skin cells of ALS patients can be differentiated into motor neurons. In 2009, he was selected as one of 50 Howard Hughes Medical Institute Early Career Scientists who will receive six years of dedicated support to conduct transformative research in using both human embryonic stem cells and iPS cells in ALS study and treatment.

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Supporting publications

Cell
Cell : Stem Cell
Trends in Pharmacological Sciences
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