Stem Cell : Programming and Reprogramming

Conference Title

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Speaker

Kathrin Plath

Kathrin PlathBorn in Germany, Kathrin Plath earned her doctorate degree in cell biology from Harvard Medical School and Humboldt University in Berlin studying how the signal sequence of secretory proteins is recognized by the translocation channel in the endoplasmic reticulum membrane. She received fellowships from the Life Sciences Research Foundation and the Leukemia and Lymphoma Foundation for her post-doctoral training at the University of California, San Francisco and at the Whitehead Institute at MIT, Cambridge. Her postdoctoral research focused on the function of Polycomb Group proteins, a family of transcriptional repressors, in embryonic stem cells and the process of X chromosome inactivation. She joined the faculty at the University of California Los Angeles in 2006 as an Assistant Professor of Biological Chemistry and was promoted to Associate Professor in 2011. Her research concerns mechanisms of transcription factor-induced reprogramming to the pluripotent state, particularly as it concerns chromatin states and reprogramming factor engagement. She hopes that this work will reveal what in chromatin it is that confers the stability to the differentiated cell identity versus the dynamic capabilities of pluripotentcells. At the UCLA Broad Stem Cell Research Center, she also participates in initiatives to test induced pluripotent stem (iPS) cells for clinical applications and has begun to use human iPS cells to study diseases caused by abnormalities in chromatin regulation.

Kathrin Plath serves on editorial boards of several journals including CELL, Cell Research, Stem Cells, Stem Cell Reviews and Reports, Cellular Reprogramming, edited a book on Stem Cell biology for Landes Biosciences with Eran Meshorer, and is a member of the Board of Directors of the International Society for Stem Cell Research. She also received the NIH Director’s New Innovator Award in 2007 and a CIRM Young Investigator Award in 2008.

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Supporting publications

Cell
Cell : Stem Cell
Trends in Pharmacological Sciences
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